ELISA TLK1 anti-

Quantity :100µL Clone Number: Aliases:PKU beta antibody; PKU-beta antibody; serine threonine protein kinase antibody; Serine/threonine protein kinase tousled like 1 antibody; Serine/threonine-protein kinase tousled-like 1 antibody; SNARE protein kinase SNAK antibody; Tlk1 antibody; TLK1_ antibody; Tousled like kinase 1 antibody; Tousled-like kinase 1 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9UKI8 Immunogen:SyntheQuantityd peptide derived from internal of TLK1. Raised in:Rabbit Reactivity: Tested Applications:ELISA, WB; WB:1:500-1:3000 Background:Rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S-phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regµLate processes involved in chromatin assembly. Isoform 3 phosphorylates and enhances the stability of the t-SNARE SNAP23, aµgmenting its assembly with syntaxin. Isoform 3 protects the cells from the ionizing radiation by facilitating the repair of DSBs. In vitro, phosphorylates histone H3 at 'Ser-10'. Yamakawa A., Gene 202:193-201(1997). Sillje H.H.W., EMBO J. 18:5691-5702(1999). Cabaniols J.-P., Mol. Biol. Cell 10:4033-4041(1999). Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:TLK1 Research Areas:Epigenetics and Nuclear Signaling;Signal transduction