ELISA USP2 anti-
Quantity :50µL
Clone Number:
Aliases:41 kDa ubiquitin specific protease antibody; 41 kDa ubiquitin-specific protease antibody; Deubiquitinating enzyme 2 antibody; Ubiquitin carboxyl terminal hydrolase 2 antibody; Ubiquitin carboxyl-terminal hydrolase 2 antibody; ubiquitin specific peptidase 2 antibody; Ubiquitin specific processing protease 2 antibody; Ubiquitin specific protease 12 antibody; Ubiquitin specific protease 9 antibody; Ubiquitin specific protease, 41kD antibody; Ubiquitin thioesterase 2 antibody; Ubiquitin thiolesterase 2 antibody; Ubiquitin-specific-processing protease 2 antibody; Ubiquitin-specific-processing protease testis antibody; UBP-t antibody; UBP2_ antibody; UBP41 antibody; USP2 antibody; USP9 antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens ()
UniProt ID:O75604
Immunogen:Fusion protein of USP2
Raised in:Rabbit
Reactivity:, Mouse, Rat
Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:50-1:200
Background:This gene encodes a member of the family of de-ubiquitinating enzymes, which belongs to the peptidase C19 superfamily. The encoded protein is a ubiquitin-specific protease which is required for TNF-alpha (tumor necrosis factor alpha) -induced NF-kB (nuclear factor kB) signaling. This protein deubiquitinates polyubiquitinated target proteins such as fatty acid synthase, murine double minute 2 (MDM2), MDM4/MDMX and cyclin D1. MDM2 and MDM4 are negative regµLators of the p53 tumor suppressor and cyclin D1 is required for cell cycle G1/S transition. MµLtiple alternatively spliced transcript variants encoding different isoforms have been identified.
Clonality:Polyclonal
Isotype:IgG
Purification Method:Antigen affinity purification
Conjµgate:Non-conjµgated
Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:USP2
Research Areas:Epigenetics and Nuclear Signaling;Cell biology
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Référence interne:
CSB-PA155084
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