ELISA Phospho-PAK2 (Ser197) anti-

Quantity :100µL Clone Number: Aliases:C-t-PAK2 antibody; CB422 antibody; EC 2.7.11.1 antibody; Gamma PAK antibody; Gamma-PAK antibody; hPAK65 antibody; Kinase antibody; p21 (CDKN1A) activated kinase 2 antibody; p21 (CDKN1A)-activated kinase 2a antibody; p21 activated kinase 2 antibody; p21 protein (Cdc42/Rac)-activated kinase 2 antibody; p21 protein Cdc42 Rac activated kinase 2 antibody; p21-activated kinase 2 antibody; p21-activated kinase; 65-KD antibody; p21-activated protein kinase I antibody; p21CDKN1A activated kinase 2 antibody; p27 antibody; p34 antibody; p58 antibody; p65PAK antibody; PAK 2 antibody; PAK-2 antibody; PAK-2p34 antibody; Pak2 antibody; PAK2_ antibody; PAK65 antibody; PAKgamma antibody; S6 H4 kinase antibody; S6/H4 kinase antibody; Serine threonine protein kinase PAK 2 antibody; Serine/threonine protein kinase PAK 2 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q13177 Immunogen:Peptide sequence around phosphorylation site of Serine 197(T-R-S(p)-V-I) derived from PAK2. Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, IHC; IHC:1:50-1:100 Background: The activated kinase acts on a variety of targets. Likely to be the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway. Activated by CDC42 and RAC1. Involved in dissolution of stress fibers and reorganization of focal complexes. Involved in regµLation of microtubµLe biogenesis throµgh phosphorylation of TBCB. Activity is inhibited in cells undergoing apoptosis, potentially due to binding of CDC2L1 and CDC2L2. Martin G.A., EMBO J. 14:1970-1978(1995). The MGC Project Team; Genome Res. 14:2121-2127(2004). Olsen J.V., Cell 127:635-648(2006). Clonality:Polyclonal Isotype:IgG Purification Method:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjµgates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:PAK2 Research Areas:Cancer;Cell biology;Microbiology?Signal transduction