ELISA SLC7A11 anti-

Quantity :50µL Clone Number: Aliases:Amino acid transport system xc xCT antibody antibody; Amino acid transport system xc- antibody; Calcium channel blocker resistance protein CCBR1 antibody; Calcium channel blocker resistance protein CCBR1 antibody antibody; CCBR1 antibody; Cysteine/glutamate transporter antibody antibody; Cystine/glutamate transporter antibody; OTTHUMP00000164578 antibody; SLC7A11 antibody; Solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 antibody; solute carrier family 7 antibody; Solute carrier family 7 member 11 antibody; Solute carrier family 7, (cationic amino acid transporter, y+ system) member 11 antibody; SYSTEM Xc(-) TRANSPORTER-RELATED PROTEIN antibody; xCT antibody; XCT_ antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9UPY5 Immunogen:Synthetic peptide of SLC7A11 Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, WB, IHC; ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:20-1:100 Background:This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resµLting in neuronal cell death. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:SLC7A11 Research Areas:Cancer;Cell biology;Metabolism;Signal transduction