ELISA UBA2 anti-

Quantity :100µL Clone Number: Aliases:Anthracycline associated resistance ARX antibody; Anthracycline-associated resistance ARX antibody; ARX antibody; FLJ13058 antibody; HRIHFB2115 antibody; SAE 2 antibody; SAE2 antibody; SAE2_ antibody; SUMO 1 activating enzyme subunit 2 antibody; SUMO activating enzyme subunit 2 antibody; SUMO-activating enzyme subunit 2 antibody; UBA2 antibody; UBA2 ubiquitin activating enzyme E1 homolog antibody; Ubiquitin like 1 activating enzyme E1B antibody; Ubiquitin like modifier activating enzyme 2 antibody; Ubiquitin-like 1-activating enzyme E1B antibody; UBLE1B antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9UBT2 Immunogen:SyntheQuantityd peptide derived from C-terminal of Uba2. Raised in:Rabbit Reactivity: Tested Applications:ELISA, WB, IHC; WB:1:500-1:3000, IHC:1:50-1:100 Background:The heterodimer acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Mark H. L. Lambermon, Mol. Cell. Biol., Jun 2002; 22: 4346 - 4357. Kyoung-Seok Ryu, J. Biol. Chem., Sep 2003; 278: 36621 - 36627. R. Jrgen Dohmen, J. Biol. Chem., JµL 1995; 270: 18099. Yoshiaki Azuma, FASEB J, Jun 2001; 10.1096. Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:UBA2 Research Areas:Cell biology