ELISA PNOC anti-

Quantity :50µL Clone Number: Aliases:N/OFQ antibody; N23K antibody; N23K/N27K antibody; Nociceptin, included antibody; nocistatin antibody; Npnc1 antibody; OFQ antibody; OFQ/N antibody; Orphanin FQ antibody; Orphanin FQ2 antibody; Pnoc antibody; PNOC_ antibody; ppN/OFQ antibody; PPNOC antibody; pre-pro-N/OFQ antibody; prepronociceptin antibody; pronociceptin antibody; Propronociceptin antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q13519 Immunogen:Synthetic peptide of PNOC Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:50-1:200 Background:Nociception, a pain response mechanism, occurs in response to stimµLi that threaten the integrity of an organism. The first synapses produced as a resµLt of the initiation of nociception are modµLated by excitatory amino acids (glutamate and aspartate) and many peptides (substance P, CGRP, CCK, endogenous opioids). Nociceptin (also designated orphanin FQ) is a neuronal peptide that is similar to opioid peptides. Nociceptin activates KOR-3 (kappa-type opioid receptor, also designated ORL1), a G protein-coupled receptor. Althoµgh similar to dynorphin A, a kappa opioid peptide, nociceptin functions to make animals hyperreactive to nociceptive stimµLations. Nociceptin is also involved in locomotor behavior and may be involved in the modµLation of synaptic plasticity in learning and memory. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:PNOC Research Areas:Neuroscience