ELISA TP53INP1 anti-

Quantity :50µL Clone Number: Aliases:DKFZp434M1317 antibody; FLJ22139 antibody; p53 damage inducible nuclear protein 1 antibody; p53 dependent damage inducible nuclear protein 1 antibody; p53 inducible nuclear protein 1 antibody; p53 inducible p53DINP1 antibody; p53-dependent damage-inducible nuclear protein 1 antibody; p53DINP1 antibody; SIP antibody; Stress induced protein antibody; Stress-induced protein antibody; T53I1_ antibody; Teap antibody; TP53 DINP1 antibody; TP53 INP1 antibody; TP53DINP1 antibody; TP53INP1 antibody; TP53INP1A antibody; TP53INP1B antibody; Tumor protein p53 inducible nuclear protein 1 antibody; Tumor protein p53-inducible nuclear protein 1 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q96A56 Immunogen:Synthetic peptide of TP53INP1 Raised in:Rabbit Reactivity: Tested Applications:ELISA, WB, IHC; ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:50-1:200 Background:TP53INP1 (tumor protein p53-inducible nuclear protein 1), also known as p53DINP1, SIP or Teap, is a 240 amino acid protein that localizes to nuclear bodies and exists as two alternatively spliced isoforms, designated p53DINP1a and p53DINP1b. Expressed ubiquitously with higher expression in testis, pancreas and spleen tissue, TP53INP1 functions in response to double-stranded DNA breaks and regµLates p53-mediated apoptosis, specifically by phosphorylating p53 at Ser 46, an event that leads to cell death. Additionally, TP53INP1 is thoµght to interact with p73 and may be involved in the regµLation of p73-controlled cell cycle progression. TP53INP1 expression is downregµLated in pancreatic ductal adenocarcinomas, sµggesting that, via its ability to induce cell death, TP53INP1 plays a role in tumor suppression. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:TP53INP1 Research Areas:Cancer;Cell biology