ELISA ZNF423 Antibody, HRP

Quantity :50µL Clone Number: Aliases:Early B cell factor associated zinc finger protein antibody; Ebfaz antibody; hOAZ antibody; JBTS19 antibody; KIAA0760 antibody; NPHP14 antibody; Nur12 antibody; OAZ antibody; OLF 1/EBF associated zinc finger antibody; OLF1/EBF associated zinc finger protein antibody; Olf1/EBF-associated zinc finger protein antibody; Roaz antibody; Smad and Olf interacting zinc finger protein antibody; Smad- and Olf-interacting zinc finger protein antibody; Zfp104 antibody; ZFP423 antibody; zinc finger protein 423, mouse, homolog of antibody; Zinc finger protein 423 antibody; ZN423_ antibody; ZNF423 antibody; ZNF423 zinc finger protein 423 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q2M1K9 Immunogen:Peptide sequence from Zinc finger protein 423 protein (39-57AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Transcription factor that can both act as an activator or a repressor depending on the context. Plays a central role in BMP signaling and olfactory neurogenesis. Associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved in terminal olfactory receptor neurons differentiation; this interaction preventing EBF1 to bind DNA and activate olfactory-specific genes. Involved in olfactory neurogenesis by participating in a developmental switch that regµLates the transition from differentiation to maturation in olfactory receptor neurons. Controls proliferation and differentiation of neural precursors in cerebellar vermis formation. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity Purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ZNF423 Research Areas:Epigenetics and Nuclear Signaling; Neuroscience; Signal transduction