ELISA VDAC1 Antibody, Biotin

Quantity :50µL Clone Number: Aliases:N2441 antibody; OMP2 antibody; POR1 antibody; hVDAC1 antibody; MGC111064 antibody; Mitochondrial Porin antibody; Outer mitochondrial membrane protein porin 1 antibody; Plasmalemmal porin antibody; Porin 31HL antibody; Porin 31HM antibody; VDAC antibody; VDAC-1 antibody; Vdac1 antibody; VDAC1_ antibody; Voltage dependent anion channel 1 antibody; Voltage dependent anion selective channel protein 1 antibody; Voltage-dependent anion-selective channel protein 1 antibody; YNL055C antibody; YNL2441C antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P21796 Immunogen:Peptide sequence from Voltage-dependent anion-selective channel protein 1 protein (32-59AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Forms a channel throµgh the mitochondrial outer membrane and also the plasma membrane. The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecµLes; in the plasma membrane it is involved in cell volume regµLation and apoptosis. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective (PubMed:11845315, PubMed:18755977, PubMed:20230784, PubMed:8420959). May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis (PubMed:15033708, PubMed:25296756). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:VDAC1 Research Areas:Isotype/Loading Controls; Cancer; Tags & Cell Markers; Metabolism; Signal transduction