ELISA USP14 Antibody, Biotin

Quantity :50µg Clone Number: Aliases:Deubiquitinating enzyme 14 antibody; TGT antibody; tRNA guanine transglycosylase 60 kD subunit antibody; tRNA guanine transglycosylase antibody; Ubiquitin carboxyl terminal hydrolase 14 antibody; Ubiquitin carboxyl-terminal hydrolase 14 antibody; Ubiquitin specific peptidase 14 antibody; Ubiquitin specific processing protease 14 antibody; Ubiquitin specific protease 14 antibody; Ubiquitin thiolesterase 14 antibody; Ubiquitin-specific-processing protease 14 antibody; UBP14_ antibody; USP 14 antibody; USP14 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P54578 Immunogen:Recombinant Ubiquitin carboxyl-terminal hydrolase 14 protein (1-494AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticµLum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticµLum proteins via interaction with ERN1. Indispensable for synaptic development and function at neuromuscµLar junctions (NMJs). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:USP14 Research Areas:Epigenetics and Nuclear Signaling; Cell biology