ELISA U2AF2 Antibody, FITC
Quantity :50µg
Clone Number:
Aliases:hU2AF(65) antibody; hU2AF65 antibody; Splicing factor U2AF 65 kDa subunit antibody; U2 (RNU2) small nuclear RNA auxiliary factor 2 antibody; U2 auxiliary factor 65 kDa subunit antibody; U2 small nuclear ribonucleoprotein auxiliary factor (65kD) antibody; U2 small nuclear RNA auxiliary factor 2 antibody; U2 snRNP auxiliary factor large subunit antibody; U2af2 antibody; U2AF2_ antibody; U2AF65 antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens ()
UniProt ID:P26368
Immunogen:Recombinant Splicing factor U2AF 65 kDa subunit protein (124-246AA)
Raised in:Rabbit
Reactivity:
Tested Applications:
Background:Necessary for the splicing of pre-mRNA. By recruiting PRPF19 and the PRP19C/Prp19 complex/NTC/Nineteen complex to the RNA polymerase II C-terminal domain (CTD), and thereby pre-mRNA, may couple transcription to splicing (PubMed:21536736). Induces cardiac troponin-T (TNNT2) pre-mRNA exon inclusion in muscle. RegµLates the TNNT2 exon 5 inclusion throµgh competition with MBNL1. Binds preferentially to a single-stranded structure within the polypyrimidine tract of TNNT2 intron 4 during spliceosome assembly. Required for the export of mRNA out of the nucleus, even if the mRNA is encoded by an intron-less gene. Represses the splicing of MAPT/Tau exon 10.
Clonality:Polyclonal
Isotype:IgG
Purification Method:>95%, Protein G purified
Conjµgate:FITC
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:U2AF2
Research Areas:Epigenetics and Nuclear Signaling
Référence interne:
CSB-PA025408LC01HU
URL de site web:
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