ELISA TUSC3 Antibody, Biotin

Quantity :50µg Clone Number: Aliases:TUSC3 antibody; N33Tumor suppressor candidate 3 antibody; Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TUSC3 antibody; Oligosaccharyl transferase subunit TUSC3 antibody; Magnesium uptake/transporter TUSC3 antibody; Protein N33 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q13454 Immunogen:Recombinant Tumor suppressor candidate 3 protein (42-196AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Acts as accessory component of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. Involved in N-glycosylation of STT3B-dependent substrates. Specifically required for the glycosylation of a subset of acceptor sites that are near cysteine residues; in this function seems to act redundantly with MAGT1. In its oxidized form proposed to form transient mixed disµLfides with a glycoprotein substrate to facilitate access of STT3B to the unmodified acceptor site. Has also oxidoreductase-independent functions in the STT3B-containing OST complex possibly involving substrate recognition. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:TUSC3 Research Areas:Cancer; Tags & Cell Markers