ELISA TRAF3 anti-

Quantity :50µg Clone Number: Aliases:CAP 1 antibody; CAP-1 antibody; CAP1 antibody; CD40 associated protein 1 antibody; CD40 binding protein antibody; CD40 bp antibody; CD40 receptor associated factor 1 antibody; CD40 receptor-associated factor 1 antibody; CD40-binding protein antibody; CD40BP antibody; CRAF 1 antibody; CRAF1 antibody; IIAE5 antibody; LAP 1 antibody; LAP1 antibody; LMP1 associated protein antibody; LMP1-associated protein 1 antibody; MIPT3 antibody; TNF receptor associated factor 3 antibody; TNF receptor-associated factor 3 antibody; TRAF 3 antibody; Traf3 antibody; TRAF3_ antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q13114 Immunogen:Recombinant TNF receptor-associated factor 3 protein (1-40AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, WB, IF; Recommended dilution: WB:1:200-1:2000, IF:1:50-1:200 Background:RegµLates pathways leading to the activation of NF-kappa-B and MAP kinases, and plays a central role in the regµLation of B-cell survival. Part of signaling pathways leading to the production of cytokines and interferon. Required for normal antibody isotype switching from IgM to IgG. Plays a role T-cell dependent immune responses. Plays a role in the regµLation of antiviral responses. Is an essential constituent of several E3 ubiquitin-protein ligase complexes. May have E3 ubiquitin-protein ligase activity and promote \\\'Lys-63\\\'-linked ubiquitination of target proteins. Inhibits activation of NF-kappa-B in response to LTBR stimµLation. Inhibits TRAF2-mediated activation of NF-kappa-B. Down-regµLates proteolytic processing of NFKB2, and thereby inhibits non-canonical activation of NF-kappa-B. Promotes ubiquitination and proteasomal degradation of MAP3K14. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Non-conjµgated Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:TRAF3 Research Areas:Cancer; Immunology; Signal transduction