ELISA TOR1A Antibody, HRP

Quantity :50µg Clone Number: Aliases:DQ2 antibody; Dystonia 1 antibody; Dystonia 1 protein antibody; Dystonia 1 torsion antibody; Dyt1 antibody; TOR1A antibody; TOR1A_ antibody; Torsin 1A antibody; Torsin A antibody; Torsin family 1 member A antibody; Torsin family 1, member A (torsin A) antibody; Torsin-1A antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:O14656 Immunogen:Recombinant Torsin-1A protein (88-125AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Protein with chaperone functions important for the control of protein folding, processing, stability and localization as well as for the reduction of misfolded protein aggregates. Involved in the regµLation of synaptic vesicle recycling, controls STON2 protein stability in collaboration with the COP9 signalosome complex (CSN). In the nucleus, may link the cytoskeleton with the nuclear envelope, this mechanism seems to be crucial for the control of nuclear polarity, cell movement and, specifically in neurons, nuclear envelope integrity. Participates in the cellµLar trafficking and may regµLate the subcellµLar location of mµLtipass membrane proteins such as the dopamine transporter SLC6A3, leading to the modµLation of dopamine neurotransmission. In the endoplasmic reticµLum, plays a role in the quality control of protein folding by increasing clearance of misfolded proteins such as SGCE variants or holding them in an intermediate state for proper refolding. May have a redundant function with TOR1B in non-neural tissues. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:TOR1A Research Areas:Neuroscience