ELISA TNIK Antibody, FITC

Quantity :50µg Clone Number: Aliases:EC 2.7.11.1 antibody; KIAA0551 antibody; Tnik antibody; TNIK_ antibody; Traf2 and NCK interacting kinase antibody; Traf2 and NCK-interacting protein kinase antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9UKE5 Immunogen:Recombinant TRAF2 and NCK-interacting protein kinase protein (523-714AA) Raised in:Rabbit Reactivity: Tested Applications: Background:Serine/threonine kinase that acts as an essential activator of the Wnt signaling pathway. Recruited to promoters of Wnt target genes and required to activate their expression. May act by phosphorylating TCF4/TCF7L2. Appears to act upstream of the JUN N-terminal pathway. May play a role in the response to environmental stress. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regµLates neuronal dendrite extension and arborization during development. More generally, it may play a role in cytoskeletal rearrangements and regµLate cell spreading. Phosphorylates SMAD1 on Thr-322. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:FITC Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:TNIK Research Areas:Signal transduction