ELISA TMEM100 anti-

Quantity :50µg Clone Number: Aliases:TMEM100 antibody; Transmembrane protein 100 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9NV29 Immunogen:Recombinant Transmembrane protein 100 protein (1-55AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, IF; Recommended dilution: IF:1:50-1:200 Background:Plays a role during embryonic arterial endothelium differentiation and vascµLar morphogenesis throµgh the ACVRL1 receptor-dependent signaling pathway upon stimµLation by bone morphogenetic proteins, such as GDF2/BMP9 and BMP10. Involved in the regµLation of nociception, acting as a modµLator of the interaction between TRPA1 and TRPV1, two molecµLar sensors and mediators of pain signals in dorsal root ganglia (DRG) neurons. Mechanistically, it weakens their interaction, thereby releasing the inhibition of TRPA1 by TRPV1 and increasing the single-channel open probability of the TRPA1-TRPV1 complex. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Non-conjµgated Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:TMEM100 Research Areas:Others