ELISA TLR1 anti-

Quantity :50µg Clone Number: Aliases:CD281 antibody; CD281 antigen antibody; KIAA0012 antibody; LPRS5 antibody; rsc786 antibody; TIL antibody; TIL. LPRS5 antibody; Tlr1 antibody; TLR1_ antibody; Toll (Drosophila) homolog antibody; Toll like receptor 1 antibody; Toll-like receptor 1 antibody; Toll/interleukin-1 receptor-like protein antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q15399 Immunogen:Recombinant Toll-like receptor 1 protein (25-580AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200 Background:Participates in the innate immune response to microbial agents. Specifically recognizes diacylated and triacylated lipopeptides. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Forms the activation cluster TLR2:TLR1:CD14 in response to triacylated lipopeptides, this cluster triggers signaling from the cell surface and subsequently is targeted to the Golgi in a lipid-raft dependent pathway. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Non-conjµgated Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:TLR1 Research Areas:Immunology; Signal transduction