ELISA TIRAP anti-

Quantity :50µL Clone Number: Aliases:TIRAP antibody; MAL antibody; Toll/interleukin-1 receptor domain-containing adapter protein antibody; TIR domain-containing adapter protein antibody; Adaptor protein Wyatt antibody; MyD88 adapter-like protein antibody; MyD88-2 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P58753 Immunogen:Recombinant Toll/interleukin-1 receptor domain-containing adapter protein (1-221AA) Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200 Background:Adapter involved in TLR2 and TLR4 signaling pathways in the innate immune response. Acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, and resµLting in cytokine secretion and the inflammatory response. Positively regµLates the production of TNF-alpha and interleukin-6. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity Purified Conjµgate:Non-conjµgated Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:TIRAP Research Areas:CardiovascµLar; Immunology; Signal transduction