ELISA TERF1 Antibody, Biotin

Quantity :50µg Clone Number: Aliases:hTRF1 AS antibody; NIMA interacting protein 2 antibody; NIMA-interacting protein 2 antibody; PIN 2 antibody; PIN2 antibody; t TRF1 antibody; Telomeric protein Pin2 antibody; Telomeric protein Pin2/TRF1 antibody; Telomeric repeat binding factor (NIMA interacting) 1 antibody; Telomeric repeat binding factor 1 antibody; Telomeric repeat binding protein 1 antibody; Telomeric repeat-binding factor 1 antibody; TERF 1 antibody; Terf1 antibody; TERF1_ antibody; TRBF 1 antibody; TRBF1 antibody; TRF 1 antibody; TRF antibody; TTAGGG repeat binding factor 1 antibody; TTAGGG repeat-binding factor 1 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P54274 Immunogen:Recombinant Telomeric repeat-binding factor 1 protein (260-439AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Binds the telomeric double-stranded 5\'-TTAGGG-3\' repeat and negatively regµLates telomere length. Involved in the regµLation of the mitotic spindle. Component of the shelterin complex (telosome) that is involved in the regµLation of telomere length and protection. Shelterin associates with arrays of double-stranded 5\'-TTAGGG-3\' repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:TERF1 Research Areas:Epigenetics and Nuclear Signaling