ELISA ST5 anti-

Quantity :50µL Clone Number: Aliases:DENND2B antibody; DENN domain containing protein 2B antibody; DENN domain-containing protein 2B antibody; DENN/MADD domain containing 2B antibody; HeLa tumor suppression 1 antibody; HTS1 antibody; p126 antibody; ST 5 antibody; ST5 antibody; ST5_ antibody; Suppression of tumorigenicity 5 antibody; Suppression of tumorigenicity 5 protein antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P78524 Immunogen:Peptide sequence from Suppression of tumorigenicity 5 protein (68-88AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200 Background:Guanine nucleotide exchange factor (GEF) which may activate RAB9A and RAB9B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. May be involved in cytoskeletal organization and tumorogenicity. Isoform 1 seems to be involved in a signaling transduction pathway leading to activation of MAPK1/ERK2. Isoform 3 may block ERK2 activation stimµLated by ABL1. Isoform 3 may alter cell morphology and cell growth. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity Purified Conjµgate:Non-conjµgated Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ST5 Research Areas:Cancer; Signal transduction