ELISA SRGN anti-

Quantity :50µL Clone Number: Aliases:Chondroitin sµLfate proteoglycan core protein antibody; Cytolytic granµLe proteoglycan core protein antibody; FLJ12930 antibody; gp600 antibody; Hematopoetic proteoglycan core protein antibody; Mastocytoma proteoglycan core protein antibody; MGC9289 antibody; OTTHUMP00000019716 antibody; P.PG antibody; PG19 core protein antibody; Pgsg antibody; Platelet proteoglycan core protein antibody; platelet proteoglycan protein core antibody; PLATELET PROTEOGLYCAN PROTEIN CORE; PPG antibody; PPG antibody; PRG antibody; PRG1 antibody; PROTEOGLYCAN 1 antibody; proteoglycan 1; secretory granµLe antibody; Proteoglycan 10K core protein antibody; Proteoglycan peptide core protein antibody; PROTEOGLYCAN PROTEIN CORE FOR MAST CELL SECRETORY GRANµLE antibody; secretory granµLe proteoglycan 1 antibody; Secretory granµLe proteoglycan core peptide antibody; Secretory granµLe proteoglycan core protein antibody; Serglycin antibody; serglycin proteoglycan antibody; Sgc antibody; Srgn antibody; SRGN_ antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P10124 Immunogen:Recombinant Serglycin protein (28-158AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200 Background:Plays a role in formation of mast cell secretory granµLes and mediates storage of various compounds in secretory vesicles. Required for storage of some proteases in both connective tissue and mucosal mast cells and for storage of granzyme B in T-lymphocytes. Plays a role in localizing neutrophil elastase in azurophil granµLes of neutrophils. Mediates processing of MMP2. Plays a role in cytotoxic cell granµLe-mediated apoptosis by forming a complex with granzyme B which is delivered to cells by perforin to induce apoptosis. RegµLates the secretion of TNF-alpha and may also regµLate protease secretion. Inhibits bone mineralization. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity Purified Conjµgate:Non-conjµgated Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:SRGN Research Areas:Cell biology; Metabolism; Signal transduction