ELISA SLC22A2 Antibody, Biotin

Quantity :50µg Clone Number: Aliases:SLC22A2 antibody; OCT2Solute carrier family 22 member 2 antibody; Organic cation transporter 2 antibody; hOCT2 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:O15244 Immunogen:Recombinant Solute carrier family 22 member 2 protein (48-135AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Mediates tubµLar uptake of organic compounds from circµLation. Mediates the influx of agmatine, dopamine, noradrenaline (norepinephrine), serotonin, choline, famotidine, ranitidine, histamin, creatinine, amantadine, memantine, acriflavine, 4-[4-(dimethylamino)-styryl]-N-methylpyridinium ASP, amiloride, metformin, N-1-methylnicotinamide (NMN), tetraethylammonium (TEA), 1-methyl-4-phenylpyridinium (MPP), cimetidine, cisplatin and oxaliplatin. Cisplatin may develop a nephrotoxic action. Transport of creatinine is inhibited by fluoroquinolones such as DX-619 and LVFX. This transporter is a major determinant of the anticancer activity of oxaliplatin and may contribute to antitumor specificity. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:SLC22A2 Research Areas:Metabolism; Signal transduction