ELISA SLC11A1 anti-

Quantity :50µg Clone Number: Aliases:LSH antibody; Natural resistance associated macrophage protein 1 antibody; Natural resistance-associated macrophage protein 1 antibody; NRAM1_ antibody; NRAMP 1 antibody; NRAMP antibody; PBC antibody; SLC11A1 antibody; Solute carrier family 11 (proton coupled divalent metal ion transporters) member 1 antibody; solute carrier family 11 (sodium/phosphate symporters) member 1 antibody; Solute carrier family 11 member 1 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P49279 Immunogen:Recombinant Natural resistance-associated macrophage protein 1 protein (1-58AA) Raised in:Rabbit Reactivity:, Rat Tested Applications:ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:100-1:300, IF:1:50-1:200 Background:Divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Macrophage-specific membrane transport function. Controls natural resistance to infection with intracellµLar parasites. Pathogen resistance involves sequestration of Fe(2+) and Mn(2+), cofactors of both prokaryotic and eukaryotic catalases and superoxide dismutases, not only to protect the macrophage against its own generation of reactive oxygen species, but to deny the cations to the pathogen for synthesis of its protective enzymes. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Non-conjµgated Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:SLC11A1 Research Areas:Immunology; Metabolism; Signal transduction