ELISA SIRPA anti-

Quantity :50µg Clone Number: Aliases:Signal regµLatory protein alpha type 1 antibody; Bit antibody; Brain Ig like molecµLe with tyrosine based activation motifs antibody; Brain Ig-like molecµLe with tyrosine-based activation motifs antibody; Brain immunoglobµLin like molecµLe with tyrosine based activation motifs antibody; CD172 antigen like family member A antibody; CD172 antigen-like family member A antibody; CD172a antibody; CD172a antigen antibody; Inhibitory receptor SHPS-1 antibody; Macrophage fusion receptor antibody; MFR antibody; MYD 1 antibody; Myd 1 antigen antibody; MyD-1 antigen antibody; p84 antibody; Protein tyrosine phosphatase non receptor type substrate 1 antibody; PTPNS1 antibody; SHP substrate 1 antibody; SHPS-1 antibody; SHPS1 antibody; SHPS1_ antibody; Signal regµLatory protein alpha 2 antibody; Signal regµLatory protein alpha 3 antibody; Signal regµLatory protein alpha antibody; Signal regµLatory protein alpha type 2 antibody; Signal-regµLatory protein alpha-1 antibody; Signal-regµLatory protein alpha-2 antibody; Signal-regµLatory protein alpha-3 antibody; SIRP antibody; Sirp-alpha-1 antibody; Sirp-alpha-2 antibody; Sirp-alpha-3 antibody; SIRPA antibody; SIRPalpha antibody; SIRPalpha1 antibody; SIRPalpha2 antibody; SIRPalpha3 antibody; Tyrosine phosphatase SHP substrate 1 antibody; Tyrosine protein phosphatase non receptor type substrate 1 antibody; Tyrosine-protein phosphatase non-receptor type substrate 1 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P78324 Immunogen:Recombinant Tyrosine-protein phosphatase non-receptor type substrate 1 protein (31-373AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200 Background:ImmunoglobµLin-like cell surface receptor for CD47. Acts as docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane. Supports adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment. May play a key role in intracellµLar signaling during synaptogenesis and in synaptic function (By similarity). Involved in the negative regµLation of receptor tyrosine kinase-coupled cellµLar responses induced by cell adhesion, growth factors or insµLin. Mediates negative regµLation of phagocytosis, mast cell activation and dendritic cell activation. CD47 binding prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Non-conjµgated Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:SIRPA Research Areas:Neuroscience; CardiovascµLar; Signal transduction