ELISA SIN3B anti-

Quantity :50µg Clone Number: Aliases:SIN3B antibody; KIAA0700 antibody; Paired amphipathic helix protein Sin3b antibody; Histone deacetylase complex subunit Sin3b antibody; Transcriptional corepressor Sin3b antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:O75182 Immunogen:Recombinant Paired amphipathic helix protein Sin3b protein (705-769AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC, IF; Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200 Background:Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription. With FOXK1, regµLates cell cycle progression probably by repressing cell cycle inhibitor genes expression. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Non-conjµgated Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:SIN3B Research Areas:Epigenetics and Nuclear Signaling; Cancer; Metabolism