ELISA SESN3 anti-

Quantity :50µL Clone Number: Aliases:MGC29667 antibody; OTTHUMP00000236979 antibody; OTTHUMP00000236986 antibody; SESN3 antibody; SESN3_ antibody; SEST3 antibody; Sestrin 3 antibody; Sestrin-3 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P58005 Immunogen:Recombinant Sestrin-3 protein (1-310AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200 Background:Sestrins, including sestrin-1 (PA26), sestrin-2 (Hi95), and sestrin-3, are 48 to 65 kDa cystein sµLfinyl reductases and they modµLate peroxide signaling and antioxidant defense. These proteins selectively reduce or repair hyperoxidized forms of typical 2-Cys peroxiredoxins within eukaryotes. Expression of these proteins is regµLated by p53, a tumor suppressor protein. Sestrin 3 was identified as a forkhead box O (FoxO) target gene with antioxidant activity. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity Purified Conjµgate:Non-conjµgated Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:SESN3 Research Areas:Cancer; CardiovascµLar; Cell biology; Metabolism