ELISA RBL1 anti-

Quantity :50µg Clone Number: Aliases:107 kDa retinoblastoma-associated protein antibody; CellµLar protein 107 antibody; CellµLar protein p107 antibody; CP107 antibody; MGC40006 antibody; p107 antibody; PRB1 antibody; RBL1 antibody; RBL1_ antibody; Retinoblastoma like protein 1 antibody; retinoblastoma-like 1 (p107) antibody; Retinoblastoma-like protein 1 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P28749 Immunogen:Recombinant Retinoblastoma-like protein 1 protein (201-500AA) Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, WB; Recommended dilution: WB:1:2000-1:5000 Background:Key regµLator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particµLar, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases SUV420H1 and SUV420H2, leading to epigenetic transcriptional repression. Controls histone H4 \\\'Lys-20\\\' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation. Forms a complex with adenovirus E1A and with SV40 large T antigen. May bind and modµLate functionally certain cellµLar proteins with which T and E1A compete for pocket binding. May act as a tumor suppressor. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Non-conjµgated Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:RBL1 Research Areas:Epigenetics and Nuclear Signaling; Cancer; Cell biology; Stem cells