ELISA MCF2 Antibody, Biotin

Quantity :50µL Clone Number: Aliases:MCF2 antibody; DBLProto-oncogene DBL antibody; Proto-oncogene MCF-2) [Cleaved into: MCF2-transforming protein; DBL-transforming protein] antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P10911 Immunogen:Recombinant Proto-oncogene DBL protein (705-925AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Guanine nucleotide exchange factor (GEF) that modµLates the Rho family of GTPases. Promotes the conversion of some member of the Rho family GTPase from the GDP-bound to the GTP-bound form. Isoform 1 exhibits no activity toward RHOA, RAC1 or CDC42. Isoform 2 exhibits decreased GEF activity toward CDC42. Isoform 3 exhibits a weak but significant activity toward RAC1 and CDC42. Isoform 4 exhibits significant activity toward RHOA and CDC42. The truncated DBL oncogene is active toward RHOA, RAC1 and CDC42. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity Purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:MCF2 Research Areas:Cancer; Signal transduction