ELISA DYNLL1 anti-

Quantity :50µg Clone Number: Aliases:8 kDa dynein light chain antibody; 8kDLC antibody; Cytoplasmic dynein light polypeptide antibody; DLC1 antibody; DLC8 antibody; DNCL1 antibody; DNCLC1 antibody; DYL1_ antibody; Dynein ; cytoplasmic; light chain 1 antibody; Dynein light chain 1 cytoplasmic antibody; Dynein light chain 1; cytoplasmic antibody; Dynein light chain LC8 type 1 antibody; Dynein light chain LC8-type 1 antibody; Dynein; cytoplasmic; light polypeptide 1 antibody; Dynein; light chain; LC8-type 1 antibody; DYNLL1 antibody; HDLC1 antibody; LC8 antibody; LC8a antibody; MGC126137 antibody; MGC126138 antibody; MGC72986 antibody; PIN antibody; Protein inhibitor of neuronal nitric oxide synthase antibody; Protein inhibitor of neuronal NOS antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P63167 Immunogen:Recombinant Dynein light chain 1, cytoplasmic protein (1-89AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200 Background:Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thoµght to be involved in linking dynein to cargos and to adapter proteins that regµLate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellµLar retrograde motility of vesicles and organelles along microtubµLes. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures. Binds and inhibits the catalytic activity of neuronal nitric oxide synthase. Promotes transactivation functions of ESR1 and plays a role in the nuclear localization of ESR1. RegµLates apoptotic activities of BCL2L11 by sequestering it to microtubµLes. Upon apoptotic stimµLi the BCL2L11-DYNLL1 complex dissociates from cytoplasmic dynein and translocates to mitochondria and sequesters BCL2 thus neutralizing its antiapoptotic activity. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Non-conjµgated Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:DYNLL1 Research Areas:Others