ELISA HARS anti-

Quantity :50µL Clone Number: Aliases:cytoplasmic antibody; EC 6.1.1.21 antibody; FLJ20491 antibody; HARS antibody; HisRS antibody; Histidine tRNA ligase, cytoplasmic antibody; histidine translase antibody; Histidine tRNA ligase antibody; Histidine--tRNA ligase antibody; Histidyl tRNA synthetase antibody; Histidyl-tRNA synthetase antibody; HRS antibody; histidyl tRNA synthetase homolog (HO3) mRNA complete cds antibody; SYHC_ antibody; USH3B antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P12081 Immunogen:Recombinant Histidine--tRNA ligase, cytoplasmic protein (1-180AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, WB, IHC, IP; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IP:1:200-1:2000 Background:Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a cytoplasmic enzyme which belongs to the class II family of aminoacyl-tRNA synthetases. The enzyme is responsible for the synthesis of histidyl-transfer RNA, which is essential for the incorporation of histidine into proteins. The gene is located in a head-to-head orientation with HARSL on chromosome five, where the homologous genes share a bidirectional promoter. The gene product is a frequent target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Several transcript variants encoding different isoforms have been found for this gene. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity Purified Conjµgate:Non-conjµgated Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:HARS Research Areas:Epigenetics and Nuclear Signaling; Immunology