ELISA EIF3J Antibody, HRP

Quantity :50µg Clone Number: Aliases:eIF 3 alpha antibody; eIF-3-alpha antibody; eIF3 alpha antibody; eIF3 p35 antibody; eIF3j antibody; EIF3J_ antibody; EIF3S 1 antibody; EIF3S1 antibody; Eukaryotic translation initiation factor 3 subunit 1 antibody; Eukaryotic translation initiation factor 3 subunit J antibody; Eukaryotic translation initiation factor 3; subunit 1 (alpha; 35kD) antibody; Eukaryotic translation initiation factor 3; subunit 1 alpha; 35kD antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:O75822 Immunogen:Recombinant Eukaryotic translation initiation factor 3 subunit J protein (5-115AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimµLates mRNA recruitment to the 43S PIC and scanning of the mRNA for Aµg recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. This subunit binds directly within the mRNA entry channel of the 40S ribosome to the aminoacyl (A) site. It may regµLate the interaction between the 43S PIC and mRNA. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:EIF3J Research Areas:Epigenetics and Nuclear Signaling