ELISA TFAM anti-

Quantity :100µL Clone Number: Aliases:anscription factor 6-like 1 antibody; Mitochondrial transcription factor 1 antibody; mitochondrial transcription factor A antibody; MtTF1 antibody; mtTFA antibody; TCF 6 antibody; TCF-6 antibody; TCF6 antibody; TCF6L1 antibody; TCF6L2 antibody; TCF6L3 antibody; TFAM antibody; TFAM_ antibody; Transcription factor 6 antibody; Transcription factor 6 like 2 (mitochondrial transcription factor) antibody; Transcription factor 6 like 2 antibody; Transcription factor 6-like 2 antibody; transcription factor 6-like 3 antibody; Transcription factor A, mitochondrial antibody; Transcription factor A, mitochondrial antibody; Transcription factor A, mitochondrial precursor antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q00059 Immunogen:SyntheQuantityd peptide derived from internal of TFAM. Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC, IF; IHC:1:50-1:100, IF:1:100-1:500 Background:Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regµLation. Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. Promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. Is able to unwind DNA. Bends the mitochondrial light strand promoter DNA into a U-turn shape via its HMG boxes. Required for maintenance of normal levels of mitochondrial DNA. May play a role in organizing and compacting mitochondrial DNA. Parisi M.A., Science 252:965-969(1991). Tominaga K., Biochim. Biophys. Acta 1131:217-219(1992). Fisher R.P., J. Biol. Chem. 267:3358-3367(1992). Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:TFAM Research Areas:Epigenetics and Nuclear Signaling;Cancer?CardiovascµLar;Tags & Cell Markers;Metabolism;Signal transduction