ELISA TNFRSF10B Monoclonal anti-

Quantity :100µL Clone Number: Aliases:Fas like protein; Apoptosis inducing protein TRICK2A/2B; Apoptosis inducing receptor TRAIL R2; CD 262; CD262; CD262 antigen; Cytotoxic TRAIL receptor 2; Death domain containing receptor for TRAIL/Apo 2L; Death domain containing receptor for TRAIL/Apo2L; Product Type:Monoclonal Antibody Immunogen Species: UniProt ID:O14763 Immunogen:Purified recombinant TNFRSF10B protein fragments expressed in E.coli. Raised in:Mouse Reactivity:,Mouse Tested Applications:ELISA,WB,ICC;Recommended dilution:WB:1:500-1:5000,ICC:1:50-1:200 Background:Receptor for the cytotoxic ligand TNFSF10/TRAIL.The adapter molecµLe FADD recruits caspase-8 to the activated receptor.The resµLting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B.Essential for ER stress-induced apoptosis. Clonality:Monoclonal Isotype:IgG1 Purification Method:Affinity purified Conjµgate:Non-conjµgated Buffer:Purified mouse monoclonal in PBS(pH 7.4) containing with 0.02% sodium azide,0.1mg/mLBSA and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:TNFRSF10B Research Areas:Cancer?CardiovascµLar?Cell biology;Signal transduction