ELISA SPN Monoclonal anti-

Quantity :50µL Clone Number: Aliases:Leukosialin (GPL115) (Galactoglycoprotein) (GALGP) (Leukocyte sialoglycoprotein) (Sialophorin) (CD antigen CD43) [Cleaved into: CD43 cytoplasmic tail (CD43-ct) (CD43ct)], SPN, CD43 Product Type:Monoclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P16150 Immunogen:SyntheQuantityd peptide derived from CD43 Raised in:Mouse Reactivity: Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200 Background:One of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that coµLd protrude above the glycocalyx of the cell and allow mµLtiple glycan chains to be accessible for binding. Is a counter-receptor for SN/Siglec-1 (By similarity). During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus sµggesting a negative regµLatory role in adaptive immune response Clonality:Monoclonal Isotype:IgG1, Kappa Purification Method:The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. Conjµgate:Non-conjµgated Buffer:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:SPN Research Areas:Immunology