ELISA Recombinant Interleukin-22 protein(IL22) (Active)

Quantity:100µg. Research Areas:Immunology Uniprot NO.:Q9GZX6 Uniprot Entry Name:IL22_ Gene Names:IL22,ILTIF,ZCYTO18,UNQ3099/PRO10096 Species:Homo sapiens () Source:E.Coli Expression Region:34-179aa Sequence:M+APISSHCRL DKSNFQQPYI TNRTFmLAKE ASLADNNTDV RLIGEKLFHG VSMSERCYLM KQVLNFTLEE VLFPQSDRFQ PYMQEVVPFL ARLSNRLSTC HIEGDDLHIQ RNVQKLKDTV KKLGESGEIK AIGELDLLFM SLRNACI Protein Description:FµLl Length of Mature Protein Tag Info:Tag-Free Mol. Weight:16.9 kDa Biological_Activity:FµLly biologically active when compared to standard. The ED50 as determined by inducing IL-10 secretion of COLO 205 cells is less than 0.3 ng/mL, corresponding to a specific activity of ? 3.3 × 106 IU/mg. Purity:>97% as determined by SDS-PAGE and HPLC. Endotoxin:Less than 1.0 EU/µg as determined by LAL method. Form:Lyophilized powder Buffer:Lyophilized from a 0.2 µm filtered PBS, pH 5.0 Reconstitution:We recommend that this vial be briefly centrifµged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our defaµLt final concentration of glycerol is 50%. Customers coµLd use it as reference. Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week. Alternative Name/ Alias:IL-22, IL-10-related T-cell-derived-inducible factor, IL-TIF Relevance:Cytokine that contributes to the inflammatory response in vivo. PubMed ID:10954742; 11197690; 10875937; 12975309; 15489334; 15340161; 11856845; 15983417; 18599299 Function:Cytokine that contributes to the inflammatory response in vivo. Involvement in disease: SubcellµLar Location:Secreted Protein Families:IL-10 family Tissue Specificity: Paythway:Jak-STATsignalingpathway HGNC Database Link:https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=HGNC:14900 UniGene Database Link:https://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=287369 KEGG Database Link:https://www.genome.jp/dbget-bin/www_bget?hsa:50616 STRING Database Link:https://string-db.org/network/9606.ENSP00000329384 OMIM Database Link:https://www.omim.org/entry/605330605330605330