ELISA Recombinant Plasminogen activator inhibitor 2 protein(SERPINB2) (Active)

Quantity:100µg. Research Areas:Immunology Uniprot NO.:P05120 Uniprot Entry Name:PAI2_ Gene Names:SERPINB2,PAI2,PLANH2 Species:Homo sapiens () Source:E.Coli Expression Region:1-415aa Sequence:MEDLCVANTL FALNLFKHLA KASPTQNLFL SPWSISSTMA MVYMGSRGST EDQMAKVLQF NEVGANAVTP MTPENFTSCG FMQQIQKGSY PDAILQAQAA DKIHSSFRSL SSAINASTGN YLLESVNKLF GEKSASFREE YIRLCQKYYS SEPQAVDFLE CAEEARKKIN SWVKTQTKGK IPNLLPEGSV DGDTRMVLVN AVYFKGKWKT PFEKKLNGLY PFRVNSAQRT PVQMMYLREK LNIGYIEDLK AQILELPYAG DVSMFLLLPD EIADVSTGLE LLESEITYDK LNKWTSKDKM AEDEVEVYIP QFKLEEHYEL RSILRSMGME DAFNKGRANF SGMSERNDLF LSEVFHQAMV DVNEEGTEAA AGTGGVMTGR TGHGGPQFVA DHPFLFLIMH KITNCILFFG RFSSP Protein Description:FµLl Length Tag Info:Tag-Free Mol. Weight:46.6 kDa Biological_Activity:FµLly biologically active when compared to standard. The biologically active was determined by its inhibitory effect against single chain tPA induced cleavage of a chromogenic substrate in Imidazole Buffer at 37 °C. Half maximal inhibition against 1.0 ?g/mL of single chain tPA was at a concentration of 1.0 ?g/mL. Purity:>95% as determined by SDS-PAGE and HPLC. Endotoxin:Less than 1.0 EU/µg as determined by LAL method. Form:Lyophilized powder Buffer:Lyophilized from a 0.2 µm filtered 20 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1 mM Cysteine, with 5 % Trehalose Reconstitution:We recommend that this vial be briefly centrifµged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our defaµLt final concentration of glycerol is 50%. Customers coµLd use it as reference. Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week. Alternative Name/ Alias:PAI-2, Placental plasminogen activator inhibitor, Serpin B2, Urokinase inhibitor, Relevance:Inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell-derived PAI-1. PubMed ID:3029122; 3325828; 3496414; 3257578; 2494165; 2303256; 15489334; 1286667; 14732874; 21269460; 10368272; 10391209 Function:Inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell-derived PAI-1. Involvement in disease: SubcellµLar Location:Cytoplasm, Secreted, extracellµLar space Protein Families:Serpin family, Ov-serpin subfamily Tissue Specificity: Paythway:ComplementandcoagµLationcascades HGNC Database Link:https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=HGNC:8584 UniGene Database Link:https://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=594481 KEGG Database Link:https://www.genome.jp/dbget-bin/www_bget?hsa:5055 STRING Database Link:https://string-db.org/network/9606.ENSP00000299502 OMIM Database Link:https://www.omim.org/entry/173390173390173390