ELISA ZFYVE19 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Key regµLator of abscission step in cytokinesis: part of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellµLar chromosome bridges and accumµLation of DNA damage. Together with CHMP4C, required to retain abscission-competent VPS4(VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis. Deactivation of AURKB resµLts in dephosphorylation of CHMP4C followed by its dissociation from ZFYVE19/ANCHR and VPS4 and subsequent abscission. Immunogen:zinc finger, FYVE domain containing 19 Synonyms:FLJ14840, MPFYVE, ZFYVE19 Observed MW:52 kDa Uniprot ID:Q96K21 Reactivity: Tested Application:ELISA, WB, IHC Recommended dilution:WB: 1:1000-1:10000; IHC: 1:20-1:200 Gene ID:84936 Research Area:Metabolism