ELISA ZFP36L2 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:mRNA-binding protein that plays a key role in self-renewal of erythroid cells in response to glucocorticoids. Specifically binds to the AU-rich element(ARE) in the 3'-UTR of target mRNAs, promoting their deadenylation and degradation(PubMed:14981510). Specifically expressed in burst-forming unit-erythroid(BFU-E) progenitors in response to glucocorticoids and acts as a negative regµLator of erythroid cell differentiation: promotes self-renewal of erythroid cells by binding mRNAs that are induced or highly expressed during terminal erythroid differentiation and promotes their degradation, preventing erythroid cell differentiation. Down-regµLated during erythroid differentiation from the BFU-E stage, stabilizing mRNAs required for terminal differentiation(By similarity). Immunogen:zinc finger protein 36, C3H type-like 2 Synonyms:BRF2, Butyrate response factor 2, EGF response factor 2, ERF 2, ERF2, Protein TIS11D, RNF162C, TIS11D, ZFP36L2 Observed MW:51 kDa Uniprot ID:P47974 Reactivity:, Mouse, Rat Tested Application:ELISA, WB Recommended dilution:WB: 1:200-1:2000 Gene ID:678 Research Area:Signal Transduction, Metabolism