ELISA ARHGEF5 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Guanine nucleotide exchange factor which activates Rho GTPases(PubMed:15601624). Strongly activates RHOA(PubMed:15601624). Also strongly activates RHOB, weakly activates RHOC and RHOG and shows no effect on RHOD, RHOV, RHOQ or RAC1(By similarity). Involved in regµLation of cell shape and actin cytoskeletal organization(PubMed:15601624). Plays a role in actin organization by generating a loss of actin stress fibers and the formation of membrane ruffles and filopodia(PubMed:14662653). Required for SRC-induced podosome formation(By similarity). Involved in positive regµLation of immature dendritic cell migration(By similarity). Immunogen:Rho guanine nucleotide exchange factor(GEF) 5 Synonyms:TIM Observed MW:60 kDa Uniprot ID:Q12774 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IHC, IP Recommended dilution:WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200 Gene ID:7984 Research Area:Signal Transduction