ELISA ARHGEF4 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Acts as guanine nucleotide exchange factor(GEF) for RHOA, RAC1 and CDC42 GTPases. Binding of APC may activate RAC1 GEF activity. The APC-ARHGEF4 complex seems to be involved in cell migration as well as in E-cadherin-mediated cell-cell adhesion. Required for MMP9 up-regµLation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression. Immunogen:Rho guanine nucleotide exchange factor(GEF) 4 Synonyms:KIAA1112 Observed MW:72 kDa Uniprot ID:Q9NR80 Reactivity:, Mouse Tested Application:ELISA, IHC, WB Recommended dilution:WB: 1:500-1:2000; IHC: 1:20-1:200 Gene ID:50649 Research Area:Neuroscience, Signal Transduction