ELISA ZC3H8 anti-

Quantity :100µL Clone Number: Aliases:Fliz1 antibody; Zc3h8 antibody; ZC3H8_ antibody; Zinc finger CCCH domain containing protein 8 antibody; Zinc finger CCCH domain-containing protein 8 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q8N5P1 Immunogen:SyntheQuantityd peptide derived from internal of ZC3H8. Raised in:Rabbit Reactivity: Tested Applications:ELISA, WB, IHC; WB:1:500-1:3000, IHC:1:50-1:100 Background:Acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5'-AGGTCTC-3' sequence within the negative cis-acting element intronic regµLatory region (IRR) of the GATA3 gene By similarity. Induces thymocyte apoptosis when overexpressed, which may indicate a role in regµLation of thymocyte homeostasis. Zhuang D.Z., Submitted (JAN-2001) to the EMBL/GenBank/DDBJ databases. The MGC Project Team, Genome Res. 14:2121-2127(2004). Hwang E.S., Immunology 106:464-469(2002). Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ZC3H8 Research Areas:Epigenetics and Nuclear Signaling