ELISA KARS Antibody, HRP

Quantity :50µg Clone Number: Aliases:CMTRIB antibody; DFNB89 antibody; EC 6.1.1.6 antibody; KARS 1 antibody; KARS 2 antibody; KARS antibody; KARS1 antibody; KARS2 antibody; KIAA0070 antibody; KRS antibody; Lysine tRNA ligase antibody; Lysine--tRNA ligase antibody; LysRS antibody; Lysyl tRNA synthetase antibody; Lysyl-tRNA synthetase antibody; SYK_ antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q15046 Immunogen:Recombinant Lysine--tRNA ligase protein (101-400AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA (PubMed:9278442, PubMed:18029264, PubMed:18272479). When secreted, acts as a signaling molecµLe that induces immune response throµgh the activation of monocyte/macrophages (PubMed:15851690). Catalyzes the synthesis of the signaling molecµLe diadenosine tetraphosphate (Ap4A), and thereby mediates disruption of the complex between HINT1 and MITF and the concomitant activation of MITF transcriptional activity (PubMed:5338216, PubMed:14975237, PubMed:19524539, PubMed:23159739). (Microbial infection) Interacts with HIV-1 virus GAG protein, facilitating the selective packaging of tRNA3(Lys), the primer for reverse transcription initiation. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:KARS Research Areas:Epigenetics and Nuclear Signaling