ELISA Phospho-MAPT (Ser262) anti-

Quantity :100µL Clone Number: Aliases:AI413597 antibody; AW045860 antibody; DDPAC antibody; FLJ31424 antibody; FTDP 17 antibody; G protein beta1/gamma2 subunit interacting factor 1 antibody; MAPT antibody; MAPTL antibody; MGC134287 antibody; MGC138549 antibody; MGC156663 antibody; MicrotubµLe associated protein tau antibody; MicrotubµLe associated protein tau isoform 4 antibody; MicrotubµLe-associated protein tau antibody; MSTD antibody; Mtapt antibody; MTBT1 antibody; MTBT2 antibody; Neurofibrillary tangle protein antibody; Paired helical filament tau antibody; Paired helical filament-tau antibody; PHF tau antibody; PHF-tau antibody; PPND antibody; PPP1R103 antibody; Protein phosphatase 1, regµLatory subunit 103 antibody; pTau antibody; RNPTAU antibody; TAU antibody; TAU_ antibody; Tauopathy and respiratory failure antibody; Tauopathy and respiratory failure, included antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P10636 Immunogen:Peptide sequence around phosphorylation site of serine 262 (I-G-S(p)-T-E) derived from Tau. Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB, IHC, IF; WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200 Background:Promotes microtubµLe assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubµLes while the N-terminus binds neural plasma membrane components, sµggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. Timm T, et al. (2003) EMBO J; 22(19): 5090-5101. Clonality:Polyclonal Isotype:IgG Purification Method:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjµgates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi Conjµgate:Non-conjµgated Buffer:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:MAPT Research Areas:Neuroscience;Signal transduction