ELISA ARHGEF1 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Seems to play a role in the regµLation of RhoA GTPase by guanine nucleotide-binding alpha-12(GNA12) and alpha-13(GNA13) subunits. Acts as GTPase-activating protein(GAP) for GNA12 and GNA13, and as guanine nucleotide exchange factor(GEF) for RhoA GTPase. Activated G alpha 13/GNA13 stimµLates the RhoGEF activity throµgh interaction with the RGS-like domain. This GEF activity is inhibited by binding to activated GNA12. Mediates angiotensin-2-induced RhoA activation. Immunogen:Rho guanine nucleotide exchange factor(GEF) 1 Synonyms:ARHGEF1, GEF1, LBCL2, LSC, P115 RHOGEF, p115RhoGEF, SUB1.5, ARHG1 Observed MW:102-110 kDa Uniprot ID:Q92888 Reactivity:, Rat Tested Application:ELISA, IHC Recommended dilution:IHC: 1:20-1:200 Gene ID:9138 Research Area:Signal Transduction, Metabolism