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ELISA ZIP kinase anti-

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Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:ZIP kinase, also named as ZIPK and Dlk, belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family and DAP kinase subfamily. ZIP kinase is a Serine/threonine kinase which acts as a positive regµLator of apoptosis. ZIP kinasephosphorylates histone H3 on 'Thr-11' at centromeres during mitosis. ZIP kinase regµLates myosin light chain phosphatase throµgh phosphorylation of MYPT1 thereby regµLating the assembly of the actin cytoskeleton, cell migration, invasiveness of tumor cells, smooth muscle contraction and neurite outgrowth. It catalyze the reaction: ATP + a protein = ADP + a phosphoprotein. Immunogen:death-associated protein kinase 3 Synonyms:DAP kinase 3, DAP like kinase, DAPK3, Dlk, ZIP kinase, ZIPK Observed MW:53kd Uniprot ID:O43293 Reactivity: Tested Application:ELISA, WB, IF Recommended dilution:WB: 1:200-1:1000; IF: 1:20-1:200 Gene ID: Research Area:

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