ELISA ZGPAT anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Transcription repressor that specifically binds the 5'-GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting the chromatin mµLtiprotein complex NuRD to target promoters. Negatively regµLates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway sµggest it may act as a tumor suppressor. Able to suppress breast carcinogenesis. Isoform 4: Antagonizes the transcription repression by isoform 1 by competing for the binding of the NuRD complex. Does not bind DNA. Immunogen:zinc finger, CCCH-type with G patch domain Synonyms:ZGPAT, ZC3HDC9, ZC3H9, KIAA1847, GPATCH6 Observed MW:57 kDa Uniprot ID:Q8N5A5 Reactivity:, Mouse Tested Application:ELISA, WB Recommended dilution:WB: 1:500-1:5000 Gene ID:84619 Research Area:Metabolism