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ELISA ZBTB38 anti-

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Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Transcriptional regµLator with bimodal DNA-binding specificity. Binds with a higher affinity to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' but can also bind to E-box elements(5'-CACGTG-3'). Can also bind specifically to a single methyl-CpG pair. Represses transcription in a methyl-CpG-dependent manner(PubMed:16354688). Plays an important role in regµLating DNA replication and common fragile sites(CFS) stability in a RBBP6-and MCM10-dependent manner; represses expression of MCM10 which plays an important role in DNA-replication(PubMed:24726359). Acts as a transcriptional activator. May be involved in the differentiation and/or survival of late postmitotic neurons(By similarity). Immunogen:zinc finger and BTB domain containing 38 Synonyms:ZBTB38, FLJ31131, FLJ35036, CIBZ, FLJ22332 Observed MW:134 kDa Uniprot ID:Q8NAP3 Reactivity: Tested Application:ELISA, WB, IHC Recommended dilution:WB: 1:500-1:5000; IHC: 1:20-1:200 Gene ID:253461 Research Area:Metabolism

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