ELISA ZAK anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20? for 12 months (Avoid repeated freeze / thaw cycles.) Background:This gene is a member of the MAPKKK family of signal transduction molecµLes and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regµLation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. Immunogen:sterile alpha motif and leucine zipper containing kinase AZK Synonyms:AZK, HCCS 4, mLK related kinase, mLK7, mLklak, mLT, mLTK, MRK, ZAK Observed MW:55 kDa, 100 kDa Uniprot ID:Q9NYL2 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IHC, IF Recommended dilution:WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:20 - 1:50 Gene ID:51776 Research Area:Signal Transduction, Metabolism