ELISA ZBTB33 Antibody, Biotin

Quantity :50µg Clone Number: Aliases:Kaiso antibody; Kaiso protein antibody; Kaiso transcription factor antibody; KAISO_ antibody; Transcriptional regµLator Kaiso antibody; ZBTB 33 antibody; Zbtb33 antibody; Zinc finger and BTB domain containing 33 antibody; Zinc finger and BTB domain-containing protein 33 antibody; Zinc finger transcription factor Kaiso antibody; ZNF 348 antibody; ZNF Kaiso antibody; ZNF348 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q86T24 Immunogen:Recombinant Transcriptional regµLator Kaiso protein (113-228AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Transcriptional regµLator with bimodal DNA-binding specificity. Binds to methylated CpG dinucleotides in the consensus sequence 5\'-CGCG-3\' and also binds to the non-methylated consensus sequence 5\'-CTGCNA-3\' also known as the consensus kaiso binding site (KBS). Recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. May contribute to the repression of target genes of the Wnt signaling pathway. May also activate transcription of a subset of target genes by the recruitment of CTNND2. Represses expression of MMP7 in conjunction with transcriptional corepressors CBFA2T3, CBFA2T2 and RUNX1T1 (PubMed:23251453). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ZBTB33 Research Areas:Epigenetics and Nuclear Signaling