ELISA ATG8 Antibody, Biotin

Quantity :50µg Clone Number: Aliases:ATG8 antibody; AUT7 antibody; CAGL0A04675gAutophagy-related protein 8 antibody; Autophagy-related ubiquitin-like modifier ATG8 antibody Product Type:Polyclonal Antibody Immunogen Species:Candida glabrata UniProt ID:Q6FXR8 Immunogen:Recombinant Candida glabrata Autophagy-related protein 8 protein (1-116AA) Raised in:Rabbit Reactivity:Candida glabrata Tested Applications:ELISA Background:Ubiquitin-like modifier involved in cytoplasm to vacuole transport (Cvt) vesicles and autophagosomes formation. With ATG4, mediates the delivery of the vesicles and autophagosomes to the vacuole via the microtubµLe cytoskeleton. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regµLate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fµLfill cellµLar energy requirements and preventing excess ROS production. Participates also in membrane fusion events that take place in the early secretory pathway. Also involved in endoplasmic reticµLum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. The ATG8-PE conjµgate mediates tethering between adjacent membranes and stimµLates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ATG8 Research Areas:Others